She encountered Kenneth again, on the day of The Disaster, while traveling with her daughter, Francesca Rossi, at the San Francisco Airport. They traveled together afterwards, through the United States and Canada, eventually reaching the Data Station in Alaska.
Upon reaching the Data Station, she, Francesca, and Kenneth were captured by Jason O'Brien who was still obsessed with finding Godshand. However, Kenneth was somehow able to make use of Simona's gifts, in tandem with their HPlus Implants, to take control of the nanotechnology that was still causing Jason's physical disabilities. He then used these nano-bots to reverse the effects of the virus. Although billions were dead, HPlus could once again be used safely.